maxxipaws maxxiSAMe Advanced SAM-e Powder Supplement - Liver, Cognitive & Joint Support for Dogs, 150g

Our eldest dachshund had a very high liver enzyme count when bloods were taken, following major gastric surgery. Our vet recommended a tablet that contained various ingredients to support the liver. The tablet brought his enzymes down, but, it is very expensive for a months supply, and on some days I would find the soggy tablet later in the day hidden near the fridge freezer. Reading reviews online, I became aware of several customers who had similar issues , and had tried the Maxxi SAMe instead with great results. Had a good read up, the SAMe quantity was identical, with silybjn too, from a different source, but also several other excellent ingredients , such as vitamin B12, B6, B1, B2 inositol, and choline. These are very important for nervous system and brain function. Plus the fact , that the tub is very generous for the money. So you get more benefit for a far more resonable cost . My dog has 1/4 scoop twice a day ,which is 1.25 gms for his weight of 6.6 kg. I purchased this tub in March and will need my next tub in July . The final clincher for this product, is the advice and customer service from the manufacturer. They have a great website with a dedicated phone line. When I phoned to discuss withholding Maxxi Cardio for a few days before his dental surgery, they were extremely knowledgeable and helpful. It's unusual, in my experience, to find people so invested in getting products that benefit pets. This is possibly because they all are pet owners and use these products themselves. I also had a very nice follow up email regarding dosage of Maxxi Joint for my younger dachshund. Milo had routine bloods taken before his dental in May, since he is almost 15 and surgery not without risk . Our vet stated that for his age, the bloods were good, and liver enzymes are now only mildly elevated, which is as expected for his age and pancreatic issues. Our vet was even more impressed with his recovery at his 10 day post op check , as were we. He is a different dog and I am convinced that introducing Maxxi Cardio (which I have also reviewed) was crucial to his well being as he had become quite weak with a heart murmur. If you are tempted to try the Maxxi Paws products, then contact with the customer service will no doubt help your decision, and give you good guidance. For us , Maxxi Same and Maxxi Cardio play a big part in our dachshund's fantastic health, and have hugely improve his quality of life .

Our old Labrador seemed to really benefit from maxxisame, it definitely helped her liver recover several times and helped her mobility and she liked the taste too. She has sadly just passed away now at 15 but we think this product has kept her going for a long time. Thank you maxxipaws.

Seems OK. We used samylin sachets before but can't get hold of them so trying this

I bought this product after my 17yr old Jack Russells blood test showed up very high liver count levels. It helped him a lot for the first 5-6 weeks and then he refused to eat anything with the powder in it. I had milk thistle drops that I was giving him with this product which he didn't mind taking. This is a good product and while he was taking it he was a different person, it started working within a few days. If you are anything like me, and would do anything for your child, then this product is a must, even just as an every day supplement. Sadly he stopped eating over Christmas while I was away on a family emergency and he became very weak and never recovered. He was put to sleep on the 10/01/25 as the liver damage was too far along. Hope this helps and that this product can buy you a bit more time with your beloved pet child.

I rescued my dog several months ago and have spent lots of time working with him to undo whatever had happened previously in his life, which unfortunately is unknown. He was making progress slowly and I was working hard with him but I felt he was lacking something, like he was just sad or a bit depressed or something. This got me thinking about a conversation I had with a close friend of mine who had depression and had used the human form of SAMe to help her. So I started to research about SAMe and looked for a K9 version and found MaxxiSAMe on the Internet. I decided to try it and I ordered a tub. Wasn't, sure if it would do anything really but after just a few weeks my dog seems much more relaxed most of the time, less fed up and less depressed. He is a lot calmer and less moody and more receptive to normal stuff. He just seems happier. This product is brilliant and has really helped speed up my dogs progress. I recommend it to anyone who is having similar experiences to myself. Thank you so much Maxxidog!

Was a great idea, BUT after nine months it clearly isn't working for my dog. So back to the more expensive Denamarin for us, and back to fighting to get my furry fatso to take tablets!

Dogs liver enzyme results are stable thanks to maxisame. Also this is a cheaper option to the supplement the vet recommended!!

A mi perro le vá fantástico. Tiene problemas con el higado y lo necessita para vivir bien.

Buon prodotto. Difficile da reperire altrove.

Kann auch von Menschen konsumiert werden... Muss nur entsprechend dosiert werden!!!

Update 10/15/2025: Hi there, me again. Now that it is 8 years later, Barney's adopted little brother Maximus is well into his senior years. He's in great shape for his age, which we estimate to be around 13 years (he's a rescue pittie), but he's started showing some signs of cognitive decline - restlessness, pacing, and panting, especially at night. We are managing his relatively mild arthritis stiffness with meds from our vet, thinking that's why he was so agitated, but the cognitive symptoms persisted. That's when I remembered how much this supplement helped our Barney all those years ago. We've been loyal to the Maxxi brand this whole time - Max gets the Omega oil and MaxxiDigest on his food daily to help with his coat and tummy (ya boy gets some serious diarrhea and gas that'll knock you out without it) - so I can't believe it took me this long to remember that MaxxiSAMe exists. Unlike Barney, Max gobbles this stuff right up with his food, no weird cheese sushi roll required. Thank you, MaxxiPaws, for continuing to put out a quality product. ---- Final Barney update 5/24/2017: This will be my final update to this review, as we unfortunately had to say goodbye to our wonderful dog Barney last week after his slow onset of degenerative myleopathy had progressed too far. I cannot say enough good things about the MaxxiDog company as they helped us find solutions to make Barney's last year+ as comfortable and happy as it could be. I truly believe that the MaxxiSAMe product had a positive effect for Barney and was key in making his last time with us a happy one, as it really seemed to help mitigate his symptoms of Canine Cognitive Dysfunction (CCD). I have changed my review to five stars to reflect this. Please continue reading below for the original review, and the other updates on how we ended up using the product. (Spoiler: The most effective way to get Barney to eat it was to do two small pumps of MaxxiOmega oil with it to make a paste, and then put the paste in American cheese like a weird little sushi roll! He never turned his nose up at this option.) Thank you again to the MaxxiDog company for your excellent product and wonderful customer service. ---- (Original review:) My dog Barney is well into his golden years and has is showing some pretty strong signs of canine cognitive dysfunction (CCD; basically, doggie dementia) such as night waking/panting, getting lost or stuck in corners, licking, digging at the floor, and fecal incontinence. So, I powered up the ol' computer and did some research. It turns out there isn't a ton you can do for it once they've got it, but there are supplements that can help manage some of the symptoms and keep it from progressing as quickly. Enter: SAMe and choline. These two seemed to pop up the most in my searches but my head was spinning about what product to buy. Well, this MaxxiSAMe stuff handily has both! Awesome! Now, a little bit about Barney - Barney has been anywhere from 77 to 90 pounds since I've known him. This dog LOVES to eat. He's not picky, either - he eats 'yard treats' (if you catch my drift) regularly, for goodness sake. He once ate a raw zucchini off the floor (and immediately threw it up, but that's beside the point). Now that we've been more careful about his portion sizes he acts like we're starving him to death (I assure you, we are not) and scavenges even more. But as soon as I put this stuff on his food, Barney went on a hunger strike. He will NOT touch the stuff. It's crazy. I even tried burying cheese in his bowl thinking he'd at least eat his way down to the cheese - NOPE. Not interested. I really wish this came in pill form. I've resorted to trying to squish the dosage up in cheese and give it to him that way, which is pretty difficult since he is on the highest dosage (1 tsp per dosage, twice a day), and the supplement needs to be inside the cheese for him to eat it. I have made some messes. I think my next attempt may involve deli meat since that won't fall apart like cheese slices... though now I have visions of Barney biting into the powder ball in the meat and causing an explosion. He's only had his full dosage(ish... the part that hasn't scattered out of the cheese all over the floor anyway) for a day or two. If I notice some improvement or come up with a better method of administration, I'll absolutely come back and edit my review. I really, really want to love this product. But for now, I give it 5 stars in theory and Barney gives it a 1 star in taste so we'll compromise and call it a 3. ---- UPDATE 4/28/2016: We went through two jars of this stuff, and multiple administration methods (since adding it straight to dry food was NOT an option). First I'll talk about the effects it has had on him, and then I will talk about how we've been giving it to him. EFFECTS: After giving him two jars of this, I didn't buy a third. After a few days of not being on it, his CCD symptoms increased fairly dramatically - walking around panting/whining at night, getting lost in corners, pooing inside, etc. He was still doing some of those things SOMETIMES, so it's possible that the timing of his symptoms was coincidental with stopping the MaxxiSAMe. However, I had forgotten just how bad his symptoms used to be, especially the night symptoms - we were all sleeping very terribly for a few days there. So I bought another jar hoping it would help him, and I think it has. We all slept through the night better the last couple of nights, anyway! This is why I've upped my rating to 4 stars (was previously 3). ADMINISTRATION: Oh boy. Well, the folks at MaxxiSAMe were kind enough to respond to my review in both email form and comment form (below) and include some ideas for getting him to take it, which is super awesome of them. Here is what we've tried, and what has and hasn't worked - 1. Paste method: Add a small amount of water to make a thick paste. Give to dog like treat. This worked for maybe a couple of weeks, and now he just turns his nose away from it when I try to give it to him this way. The MaxxiSAMe folks also suggested mixing it with something he likes, but I don't think this would work, for reasons I'll get to in a moment. 2. Soft food method: Barney was on meds that made his stomach upset for a while, so to get him to eat, I would add warm water to his dry kibble food to make it soft and appealing. I could add the MaxxiSAMe directly to the soft food and he'd eat it right up. *shrug* 3. Paste + cheese method: This is what we're doing now. I add a VERY small amount of water to make a thick paste, which I form into a ball with my fingers. Then I smash cheese around it so that none (or at least very little) of the MaxxiSAMe ball is showing. If it is showing, he will not touch the stuff - or sometimes will sort of "work" at it to get the cheese off and spit the MaxxiSAMe out. This is why I don't think it would work to mix the paste with something he enjoys: he would still know the MaxxiSAMe is in there. I think this method would work better with lunch meat, but that's not something we normally have around the house, and it goes bad faster than cheese slices. This method would probably work okay with a PillPocket type treat that has a large enough pocket. So, in conclusion, Barney still thinks the stuff is super gross which makes administration a bit of an ordeal, but I have reason to believe it might be helping his CCD so that outweighs any difficulties in giving it to him. I do still wish it came in tablet form; I picture it being like Cosequin, where it's not a coated tablet but more of a compressed powder type tablet that can be broken if needed. Thanks again to the makers of this product for supplying such a high quality product, and for responding to reviews in such a thoughtful, detailed way! ---- UPDATE 6/17/2016: After my last update, the owners of MaxxiSAMe were not content that Barney still wasn't super into the stuff. They actually sent me a free bottle of their MaxxiOmega oil to try mixing that with the MaxxiSAMe, which is super awesome of them. Turns out, it totally worked. I mix his SAMe dosage with about a pump and a half of the oil, smear it on a piece of cheese and wrap the cheese sushi-style, and he gobbles it right up. He still won't QUITE eat it without cheese (though he acts like he MIGHT when I've offered it to him), but I at least don't have to try to smash the cheese all around it to hide every speck of the MaxxiSAMe. Thank you!!

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