Up to 8 Hour Relief. Immediate Cooling Relief for Migraine & Severe Headache. Ready to use & Non-Medicinal. KOOL 'n' SOOTHE Migraine are soft gel sheets designed to provide immediate cooling relief to the severe discomfort associated with migraine and headaches. KOOL 'n' SOOTHE Migraine is safe to use with pain relief medication for maximum comfort. Ready to use and with no need for refrigeration, each gel sheet stays in place and provides up to 8 hours of cooling relief. KOOL 'n' SOOTHE Migraine sheets can be removed easily without leaving any sticky residue. For best results KOOL 'n' SOOTHE Migraine should be used at the first sign of migraine and headache. Kool 'n' Soothe - whenever you feel the need for cooling relief. Headache. High temperature. Hot flushes. Sprains. To relax. Kool 'n' Soothe is also available for children's fever.