Composition Active ingredient: dioctahedral smectite 3 g Excipients: powder for preparation of oral suspension [strawberry]: strawberry flavoring 0.032 g; dextrose monohydrate 0.721 g; sodium saccharinate 0.007 g. Pharmacological action Antidiarrheal drug, is an aluminosilicate of natural origin. Has an adsorbing effect. Stabilizes the mucous barrier of the gastrointestinal tract, forms polyvalent bonds with mucus glycoproteins, increases the amount of mucus and improves its cytoprotective properties (in relation to the negative effects of hydrogen ions of hydrochloric acid, bile salts, microorganisms and their toxins). It has selective sorption properties, which are explained by its discoid-crystalline structure; adsorbs bacteria and viruses located in the lumen of the gastrointestinal tract. Smecta in therapeutic doses does not affect intestinal motility. Diosmectite is radiolucent and does not stain stool. Aluminum in diosmectite is not absorbed from the gastrointestinal tract, including in gastrointestinal diseases accompanied by symptoms of colitis and colonopathy. Indications - Acute and chronic diarrhea (allergic, drug-induced; in case of violation of the diet and quality of food composition); - diarrhea of infectious genesis (as part of complex therapy); - symptomatic treatment of heartburn, bloating and abdominal discomfort and other symptoms of dyspepsia accompanying diseases of the gastrointestinal tract. Contraindications - Intestinal obstruction; - fructose intolerance, glucose-galactose malabsorption syndrome; - sucrase-isomaltase deficiency; - hypersensitivity to the components of the drug; - age up to 2 years. Side effects From the digestive system: rarely in clinical studies - constipation (mild, passed after dose adjustment). Allergic reactions: very rarely in routine practice - urticaria, rash, itching, Quincke's edema. Interaction When used simultaneously, Smecta can reduce the rate and extent of absorption of other drugs. It is not recommended to take the drug simultaneously with other drugs. How to take, course of administration and dosage Treatment of acute diarrhea: In adults: 3 sachets per day for 7 days. The daily dose can be doubled at the beginning of treatment. In children over 2 years old: 2 sachets per day. The daily dose can be doubled at the beginning of treatment. Before use, prepare a suspension. For adults, dissolve the contents of the sachet in 1/2 glass of water, gradually pouring in the powder and stirring it evenly. For children, the contents of the sachet, if necessary, are dissolved in a baby bottle (50 ml) and distributed over several doses during the day or mixed with any semi-liquid product (porridge, puree, compote, baby food). Overdose Severe constipation or bezoar is possible. Description A powder from white to slightly beige with a slight strawberry odor that appears when preparing the suspension. Special instructions Use with caution in patients with a history of severe chronic constipation. Adults are prescribed Smecta therapy in combination with rehydration measures if necessary. A set of rehydration measures is prescribed depending on the course of the disease, age and characteristics of the patient. The interval between taking Smecta and other drugs should be 1-2 hours. Use in pediatrics In children with acute diarrhea, the drug should be used in combination with rehydration measures. Effect on ability to drive vehicles and operate machinery No information available. Storage conditions The drug should be stored out of reach of children at a temperature not exceeding 25°C. Active substance Dioctahedral smectite Dosage form powder for preparation of suspension for oral administration